SYNOPSIS

use Bio::Ontology::OBOEngine;
my $parser = Bio::Ontology::OBOEngine->new
( -file => "gene_ontology.obo" );
my $engine = $parser->parse();

DESCRIPTION

Needs Graph.pm from CPAN.

This module replaces SimpleGOEngine.pm, which is deprecated.

FEEDBACK

Mailing Lists

User feedback is an integral part of the evolution of this and other Bioperl modules. Send your comments and suggestions preferably to the Bioperl mailing lists Your participation is much appreciated.

  [email protected]                  - General discussion
  http://bioperl.org/wiki/Mailing_lists  - About the mailing lists

Support

Please direct usage questions or support issues to the mailing list:

[email protected]

rather than to the module maintainer directly. Many experienced and reponsive experts will be able look at the problem and quickly address it. Please include a thorough description of the problem with code and data examples if at all possible.

Reporting Bugs

Report bugs to the Bioperl bug tracking system to help us keep track the bugs and their resolution. Bug reports can be submitted via the web:

  https://github.com/bioperl/bioperl-live/issues

AUTHOR

Sohel Merchant

Email: [email protected]

Address:

  Northwestern University
  Center for Genetic Medicine (CGM), dictyBase
  Suite 1206,
  676 St. Clair st
  Chicago IL 60611

CONTRIBUTOR

 Hilmar Lapp, hlapp at gmx.net
 Chris Mungall,   cjm at fruitfly.org

APPENDIX

The rest of the documentation details each of the object methods. Internal methods are usually preceded with a _

new

 Title   : new
 Usage   : $engine = Bio::Ontology::OBOEngine->new()
 Function: Creates a new OBOEngine
 Returns : A new OBOEngine object
 Args    :

init

 Title   : init()
 Usage   : $engine->init();
 Function: Initializes this Engine.
 Returns :
 Args    :

is_a_relationship

 Title   : is_a_relationship()
 Usage   : $IS_A = $engine->is_a_relationship();
 Function: Returns a Bio::Ontology::RelationshipType object for "is-a"
           relationships
 Returns : Bio::Ontology::RelationshipType set to "IS_A"
 Args    :

part_of_relationship

 Title   : part_of_relationship()
 Usage   : $PART_OF = $engine->part_of_relationship();
 Function: Returns a Bio::Ontology::RelationshipType object for "part-of"
           relationships
 Returns : Bio::Ontology::RelationshipType set to "PART_OF"
 Args    :

related_to_relationship

 Title   : related_to_relationship()
 Usage   : $RELATED_TO = $engine->related_to_relationship();
 Function: Returns a Bio::Ontology::RelationshipType object for "related-to"
           relationships
 Returns : Bio::Ontology::RelationshipType set to "RELATED_TO"
 Args    :

regulates_relationship

 Title   : regulates_relationship()
 Usage   : $REGULATES = $engine->regulates_relationship();
 Function: Returns a Bio::Ontology::RelationshipType object for "regulates"
           relationships
 Returns : Bio::Ontology::RelationshipType set to "REGULATES"
 Args    :

positively_regulates_relationship

 Title   : positively_regulates_relationship()
 Usage   : $REGULATES = $engine->positively_regulates_relationship();
 Function: Returns a Bio::Ontology::RelationshipType object for "positively_regulates"
           relationships
 Returns : Bio::Ontology::RelationshipType set to "POSITIVELY_REGULATES"
 Args    :

negatively_regulates_relationship

 Title   : negatively_regulates_relationship()
 Usage   : $REGULATES = $engine->negatively_regulates_relationship();
 Function: Returns a Bio::Ontology::RelationshipType object for "negatively_regulates"
           relationships
 Returns : Bio::Ontology::RelationshipType set to "POSITIVELY_REGULATES"
 Args    :

add_term

 Title   : add_term
 Usage   : $engine->add_term( $term_obj );
 Function: Adds a Bio::Ontology::TermI to this engine
 Returns : true if the term was added and false otherwise (e.g., if the
           term already existed in the ontology engine)
 Args    : Bio::Ontology::TermI

has_term

 Title   : has_term
 Usage   : $engine->has_term( $term );
 Function: Checks whether this engine contains a particular term
 Returns : true or false
 Args    : Bio::Ontology::TermI
           or
           Term identifier (e.g. "GO:0012345")

add_relationship_type

 Title   : add_relationship_type
 Usage   : $engine->add_relationship_type( $type_name, $ont );
 Function: Adds a new relationship type to the engine.  Use
           get_relationship_type($type_name) to retrieve.
 Returns : true if successfully added, false otherwise
 Args    : relationship type name to add (scalar)
           ontology to which to assign the relationship type

get_relationship_type

 Title   : get_relationship_type
 Usage   : $engine->get_relationship_type( $type_name );
 Function: Gets a Bio::Ontology::RelationshipI object corresponding
           to $type_name
 Returns : a Bio::Ontology::RelationshipI object
 Args    :

add_relationship

 Title   : add_relationship
 Usage   : $engine->add_relationship( $relationship );
           $engine->add_relatioship( $subject_term, $predicate_term,
                                     $object_term, $ontology );
           $engine->add_relatioship( $subject_id, $predicate_id,
                                     $object_id, $ontology);
 Function: Adds a relationship to this engine
 Returns : true if successfully added, false otherwise
 Args    : The relationship in one of three ways:
             a) subject (or child) term id, Bio::Ontology::TermI
                (rel.type), object (or parent) term id, ontology
           or
             b) subject Bio::Ontology::TermI, predicate
                Bio::Ontology::TermI (rel.type), object
                Bio::Ontology::TermI, ontology
           or
             c) Bio::Ontology::RelationshipI-compliant object

get_relationships

 Title   : get_relationships
 Usage   : $engine->get_relationships( $term );
 Function: Returns all relationships of a term, or all relationships in
           the graph if no term is specified.
 Returns : Relationship
 Args    : term id
           or
           Bio::Ontology::TermI

get_all_relationships

 Title   : get_all_relationships
 Usage   : @rels = $engine->get_all_relationships();
 Function: Returns all relationships in the graph.
 Returns : Relationship
 Args    :

get_predicate_terms

 Title   : get_predicate_terms
 Usage   : $engine->get_predicate_terms();
 Function: Returns the types of relationships this engine contains
 Returns : Bio::Ontology::RelationshipType
 Args    :

get_child_terms

 Title   : get_child_terms
 Usage   : $engine->get_child_terms( $term_obj, @rel_types );
           $engine->get_child_terms( $term_id, @rel_types );
 Function: Returns the children of this term
 Returns : Bio::Ontology::TermI
 Args    : Bio::Ontology::TermI, Bio::Ontology::RelationshipType
           or
           term id, Bio::Ontology::RelationshipType
           if NO Bio::Ontology::RelationshipType is indicated: children
           of ALL types are returned

get_descendant_terms

 Title   : get_descendant_terms
 Usage   : $engine->get_descendant_terms( $term_obj, @rel_types );
           $engine->get_descendant_terms( $term_id, @rel_types );
 Function: Returns the descendants of this term
 Returns : Bio::Ontology::TermI
 Args    : Bio::Ontology::TermI, Bio::Ontology::RelationshipType
           or
           term id, Bio::Ontology::RelationshipType
           if NO Bio::Ontology::RelationshipType is indicated:
           descendants of ALL types are returned

get_parent_terms

 Title   : get_parent_terms
 Usage   : $engine->get_parent_terms( $term_obj, @rel_types );
           $engine->get_parent_terms( $term_id, @rel_types );
 Function: Returns the parents of this term
 Returns : Bio::Ontology::TermI
 Args    : Bio::Ontology::TermI, Bio::Ontology::RelationshipType
           or
           term id, Bio::Ontology::RelationshipType
           if NO Bio::Ontology::RelationshipType is indicated:
           parents of ALL types are returned

get_ancestor_terms

 Title   : get_ancestor_terms
 Usage   : $engine->get_ancestor_terms( $term_obj, @rel_types );
           $engine->get_ancestor_terms( $term_id, @rel_types );
 Function: Returns the ancestors of this term
 Returns : Bio::Ontology::TermI
 Args    : Bio::Ontology::TermI, Bio::Ontology::RelationshipType
           or
           term id, Bio::Ontology::RelationshipType
           if NO Bio::Ontology::RelationshipType is indicated:
           ancestors of ALL types are returned

get_leaf_terms

 Title   : get_leaf_terms
 Usage   : $engine->get_leaf_terms();
 Function: Returns the leaf terms
 Returns : Bio::Ontology::TermI
 Args    :

get_root_terms()

 Title   : get_root_terms
 Usage   : $engine->get_root_terms();
 Function: Returns the root terms
 Returns : Bio::Ontology::TermI
 Args    :

get_terms

 Title   : get_terms
 Usage   : @terms = $engine->get_terms( "GO:1234567", "GO:2234567" );
 Function: Returns term objects with given identifiers
 Returns : Bio::Ontology::TermI, or the term corresponding to the
           first identifier if called in scalar context
 Args    : term ids

get_all_terms

 Title   : get_all_terms
 Usage   : $engine->get_all_terms();
 Function: Returns all terms in this engine
 Returns : Bio::Ontology::TermI
 Args    :

find_terms

 Title   : find_terms
 Usage   : ($term) = $oe->find_terms(-identifier => "SO:0000263");
 Function: Find term instances matching queries for their attributes.
           This implementation can efficiently resolve queries by
           identifier.
 Example :
 Returns : an array of zero or more Bio::Ontology::TermI objects
 Args    : Named parameters. The following parameters should be recognized
           by any implementations:
              -identifier    query by the given identifier
              -name          query by the given name

find_identically_named_terms

 Title   : find_identically_named_terms
 Usage   : ($term) = $oe->find_identically_named_terms($term0);
 Function: Find term instances where names match the query term
           name exactly
 Example :
 Returns : an array of zero or more Bio::Ontology::TermI objects
 Args    : a Bio::Ontology::TermI object

find_identical_terms

 Title   : find_identical_terms
 Usage   : ($term) = $oe->find_identical_terms($term0);
 Function: Find term instances where name or synonym
           matches the query exactly
 Example :
 Returns : an array of zero or more Bio::Ontology::TermI objects
 Args    : a Bio::Ontology::TermI object

find_similar_terms

 Title   : find_similar_terms
 Usage   : ($term) = $oe->find_similar_terms($term0);
 Function: Find term instances where name or synonym, or part of one,
           matches the query.
 Example :
 Returns : an array of zero or more Bio::Ontology::TermI objects
 Args    : a Bio::Ontology::TermI object

relationship_factory

 Title   : relationship_factory
 Usage   : $fact = $obj->relationship_factory()
 Function: Get/set the object factory to be used when relationship
           objects are created by the implementation on-the-fly.
 Example :
 Returns : value of relationship_factory (a Bio::Factory::ObjectFactoryI
           compliant object)
 Args    : on set, a Bio::Factory::ObjectFactoryI compliant object

term_factory

 Title   : term_factory
 Usage   : $fact = $obj->term_factory()
 Function: Get/set the object factory to be used when term objects are
           created by the implementation on-the-fly.
           Note that this ontology engine implementation does not
           create term objects on the fly, and therefore setting this
           attribute is meaningless.
 Example :
 Returns : value of term_factory (a Bio::Factory::ObjectFactoryI
           compliant object)
 Args    : on set, a Bio::Factory::ObjectFactoryI compliant object

graph

 Title   : graph()
 Usage   : $engine->graph();
 Function: Returns the Graph this engine is based on
 Returns : Graph
 Args    :