SYNOPSIS
palogist [ command-line options ]DESCRIPTION
palogist runs a linear regression on large imputed data sets in an efficient way.Options
Required command line options
- -p, --pheno FILE
- Read phenotype data from FILE
- -i, --info FILE
- Read SNP information from FILE (e.g. MLINFO file).
- -d, --dose FILE
- SNP predictor (e.g. MLDOSE/MLPROB) file name.
Optional command line options
- -m, --map FILE
- Map file name, containing base pair positions for each SNP.
- -n, --nids NUMBER
- Number of people to analyse.
- -c, --chrom FILE
- Chromosome (to be passed to output).
- -o, --out FILE
- Output file name (default is regression.out.txt ).
- -s, --skipd NUMBER
- How many columns to skip in predictor (dose/prob) file (default is 2).
- -t, --ntraits NUMBER
- How many traits are analysed (default is 1).
- -g, --ngpreds NUMBER
- How many predictor columns per marker (default 1 = MLDOSE; else use 2 for MLPROB).
- -a, --separat FILE
- Character to separate fields (default is space).
- -r, --score
- Use the score test.
- -e, --no-head
- Do not report header line in the output.
- -l --allcov
- Report estimates for all covariates (large outputs!).
- -b, --interaction
- Which covariate to use for interaction with SNP analysis (default is no interaction, 0).
- -k, --interaction_only
- Like --interaction but without covariate acting in interaction with SNP (default is no interaction, 0).
- -v, --mmscore FILE
- Score test in samples of related individuals. The FILE argument is the name of a file with the inverse correlation matrix. NOTE THAT THIS FEATURE IS STILL EXPERIMENTAL!
- --robust
- Report robust (a.k.a. sandwich, a.k.a. Hubert-White) standard errors.
- --help
-
Print help.
AUTHORS
Lennart C. Karssen